Job Title: Scientist
Location: Thousand Oaks, California (On-Site)
Job Summary: We are supporting a leading research organization seeking a Scientist to join a dynamic team focused on bioconjugation and next-generation antibody-based therapeutic development. This position offers the opportunity to contribute to the design, generation, purification, and characterization of complex conjugates that support discovery programs with strong scientific rigor and collaboration.
Responsibilities:
- Design, generate, purify, and characterize antibody-drug conjugates incorporating diverse linker-payload chemistries and novel payloads.
- Apply site-specific and conventional antibody conjugation strategies to support discovery efforts.
- Perform analytical characterization of conjugates, including assessment of drug-to-antibody ratio (DAR), purity, aggregation, and heterogeneity.
- Collaborate with chemistry, protein engineering, and biology teams, while documenting results, troubleshooting experiments, and communicating findings clearly.
Required:
- Doctorate degree in chemistry, chemical biology, biochemistry, or a related scientific discipline; or a master’s degree with 1–2 years of relevant laboratory experience; or a bachelor’s degree with 2–3 years of relevant laboratory experience.
- Hands-on experience with antibody-drug conjugate generation, including antibody conjugation, purification, and analytical characterization.
- Experience with analytical techniques relevant to ADC characterization, including hydrophobic interaction chromatography (HIC), size-exclusion chromatography (SEC), HPLC, and mass spectrometry.
- Familiarity with ADC quality attributes, including drug-to-antibody ratio (DAR), conjugate purity, aggregation, and heterogeneity.
- Strong analytical and problem-solving skills with the ability to independently troubleshoot experiments and interpret data.
- Strong written and verbal communication skills, with the ability to work effectively within multidisciplinary research teams.
About SSI People: With over 26 years of industry experience, SSi People has built its reputation and expertise on putting people first. Everything we do works toward delivering exceptional experience for our consultants, our clients, and our internal team. Through a genuine commitment to people in everything we do. We have developed refined processes and a stellar internal team to deliver talent quickly. More importantly, we focus on building long-term relationships, not transactions. Putting people first is just what we do well.
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